Hand powered liquid dispenser of the metering type

ABSTRACT

A hand powered liquid syringe or metering dispenser particularly for use in the veterinary medicine field comprises a pump mounted in a body having a transverse handle or grip. Standard bottles or other containers for vaccines or medicines may be mounted on a fitting secured to the body to supply the pump through a piercing tube or needle secured in the fitting. Air is supplied through the fitting to replace liquid removed from the bottle and the needle and air inlet are positioned in a manner to prevent air from being discharged from the bottle with the liquid. The pump is actuated by a squeezing action on a plunger when a handle is pressed toward the pistol grip. Check valves are provided in the inlet and outlet passages of the pump. Cannulas or other liquid discharge elements may be removed from the dispenser without requiring handling by the operator; this is accomplished by a trigger mechanism actuated by the operator&#39;&#39;s hand while he is holding the pistol grip.

United States Patent 1191 Magrath etal.

[ Aug. 6, 1974 HAND POWERED LIQUID DISPENSER OF THE METERING TYPE [75]Inventors: Joseph M. Magrath, PO. Box 148, McCook, Nebr. 69001; LeonardL. I-Iierath, Denver, C010.

[73] Assignee: Said Magrath, by said I-Iierath [22] Filed: Mar. 23, 1973[21] Appl. No.: 344,415

[56] References Cited UNITED STATES PATENTS 1,486,656 3/1924 Green,Jr..... 222/309 1,986,343 1/1935 lskyan 222/324 2,825.334 3/1958 Kas, Sr222/385 X 3,542,240 11/1970 Solowey ..12s/214 c- [57] ABSTRACT A handpowered liquid syringe or metering dispenser particularly for use in theveterinary medicine field 'comprises a pump mounted in a body having atransverse handle or grip. Standard bottles or otherconrarmns'for'vatnes or medicines may be mounted on a fitting secured tothe body to supply the pump through a piercing tube or needle secured inthe fitting. Air is supplied through the fitting to replace liquidremoved from the bottle and the needle and air inlet are positioned in amanner to prevent air from being discharged from the bottle with theliquid. The pump is actuated by a squeezing action on a plunger when ahandle is pressed toward the pistol grip. Check valves are provided inthe inlet and outlet passages of the pump. Cannulas or other liquiddischarge elements may be removed from the dispenser without requiringhandling by the operator; this is accomplished by a trigger mechanismactuated by the operators hand while he is holding the pistol grip.

14 Claims, 11 Drawing Figures PATENTED AUG 5 I974 SHEEI 1 BF 5PATENIEDMJB 81974 I sum 2 0F 5 L 4 NN a 3w iv VN 5 mm F mm M q 4 A g Hfwmm 9 \A k m. m, 1 J W mm mm Q 9 9 0m mm O E S l g Q M g a 2mm 8 Q I a IN@ 22 mm Cl wk. m mm m mm M mm ww mm K PATENTEU AUG 6:914

' SHEET 3 0F 5 HAND POWERED LIQUID DISPENSER OF THE METERING TYPE Thisinvention relates to dispensers for liquids such as vaccines andparticularly to an improved hand powered liquid dispenser of themetering type.

In treatments wherein repeated injections or applications of the samedosage of a liquid medicine or vaccine are required, it is necessary toprovide a device or devices for repeatedly discharging the same quantityof the liquid. For example, in the field of veterinary medicine, when anumber of animals must be treated oneafter another, it is time consumingto prepare and employ a separate syringe for each animal. Vaccines, forexample, are supplied in bottles from which the liquid may be withdrawnby a syringe-having a needle which will pierce the cap or seal of thebottle and allow the operator to withdraw a desired dosage of theliquid. It is desirable to provide an arrangement for utilizing a singledevice for the giving of individual treatment to a multiplicity ofanimals one after another without requiring a plurality of fillings of asyringe from a single bottle. Accordingly, it is an object of thepresent invention to provide an improved liquid dispensing device forsupplying a predetermined dosage of liquid to individuals one afteranother.

It is another object of this invention to provide an improved handpowered dispenser for discharging a preselected dose of treating liquideach time the dispenser is operated.

It is another object of this invention to provide a liquid dispenser fordischarging repeatedly a preselected quantity or dose of liquidincluding an improved arrangement for facilitating the use of a newinjection cannula or needle for each individual operation.

It is a further object of this invention to provide a hand poweredliquid dispenser including an improved arrangement for assuring thedischarge of identical doses or quantities of liquid one after another.

It is a still further object of this invention to provide an improvedhand powered dispenser for vaccines and other medicines including anarrangement for dispensing repeated equal quantities of liquid from abottle or other original container with minimal loss of liquid.

Briefly, in carrying out the objects of this invention in one embodimentthereof, a hand held and hand powered liquid dispenser is provided whichcomprises a pump or cylinder body and a transverse handle usable withthe pump actuation handle somewhat in the manner of a pistol grip. Afitting is provided on top of the body for receiving and retaining abottle or other container of the liquid to be dispensed. A piercing tubeor needle is mounted in the fitting to pass through the stopper or sealof the bottle and to provide a conducting passage between the bottle andthe pump. An air inlet passage is provided for admitting air to thebottle to replace withdrawn liquid. A predetermined minimum amount ofliquid may be trapped or retained in the dispenser regardless of thenumber of operations of the pump for dispensing doses of liquid from thebottle. A cannula or a hypodermic needle is detachably mounted on thedischarge of the device for each operation and a quick removal device isprovided which enables the operator to eject the used cannulaimmediately after use and to attach a new cannula for the next operationof the dispenser.

The features of novelty which characterize this invention are pointedout in the claims annexed to and forming a part of this specification.The invention itself, however, both as to its organization and manner ofoperation together with further objects and advantages thereof, may bestbe understood by reference to the following description taken inconnection with the accompanying drawings in which:

FIG. 1 is a perspective view of a dispenser embodying the invention witha liquid supply bottle mounted thereon;

FIG. 2 is an enlarged side elevation of the dispenser of FIG. 1;

FIG. 3 is a rear elevation view of the dispenser;

FIG. 4 is a sectional elevation view of the dispenser taken along theline 4-4 of FIG. 3;

FIG. 5 is an enlarged sectional plan view taken along the line 5-5 ofFIG. 4;

FIG. 6 is a sectional elevation view taken along the line 66 of FIG. 4;

FIG. 7 is a sectional elevation view taken along the line 7-7 of FIG. 4;

FIG. 8 is a top plan view of a cannula release slide of the dispenser ofFIGS. 1-4;

FIG. 9 is an exploded view illustrating the parts of the dispenser inposition for assembly; and

FIGS. 10 and 11 are sectional elevation views similar to FIG. 1 showingthe liquid supply and discharge positions of a modified form of liquidsource connection.

Referring now to the drawings the liquid dispenser illustrated in FIGS.1, 2 and 3 comprises an elongated main body portion 10 having atransverse handle 11 cast integrally therewith and a pump actuatinghandle 12 positioned to be pressed toward the handle 11 by squeezing thegrip by hand. A liquid source or supply illustrated as a bottle 14 ismounted on the body 10 by a fitting 15 secured on boss 16 cast as anintegral part of the body 10. The handle 12 is biased outwardly awayfrom the handle 11 by a compression spring 17 and upon squeezingtogether the handle 11 and the handle 12 liquid is discharged from thebody 10 through a check valve 19 of the so-called duck-bill type andmounted in a threaded discharge fitting l8 sealed by a gasket 18a; thevalve 19 prevents a reverse flow of liquid and the admission of air tothe body 10. A cannula or other type of discharge nozzle, indicated at20, is secured on the fitting 18 by a long taper fit which may be a Luerslip. The cannula 20 may be ejected by pressing a slide 21 forward alongthe body 10 after actuating a trigger 22 which may be easily actuated bythe back of one finger of the operator while holding the handle 11. Thisarrangement for quick release of the cannula facilitates the use of asuccessive different cannula for each one of a plurality of individualsunder treatment. The slip fit enables the operator to place a newcannula on the fitting 18 after release of the used cannula and therelease is such that it is not necessary for the operator to touch theused cannula.

The fitting 15 includes an easily actuated bottle attaching and releaselock 23. This lock may be actuated by turning in either direction torelease the bottle 14 from its seat in the fitting l5 and to lock thebottle in place. Actuation of the lock presses the seal of the bottleagainst a sealing ring in a manner to be described below.

The internal structural features of the dispenser of this invention areillustrated in FIGS. 4 through 7. The

body as illustrated in FIG. 4 is formed to provide a cylinder 24 theleft hand end of which is closed except for communication with thefitting 18 through a discharge passage 25. A piston 26 is slidablymounted in the cylinder 24 and is sealed against the wall of thecylinder by a suitable seal illustrated as an O-ring 27. The piston isconnected by a rod 28 to the actuating handle 12. The right hand end ofthe cylinder is closed by a threaded fitting 30 which includes a flange31 seated on the end of the body 10 having an outwardly projecting boss32 formed at the rear of the handle 11 on an enlarged right hand endportion of the body 10. The rod 28 is of hexagonal cross section andpasses through the closure 30 and is retained in position to hold thehandle 12 upright and in substantial alignment with the handle 11 by astop plate 33 having a hub or boss 33a and a hexagonal passage slidablyfitting the rod. Positioning tabs 34 and 35 extend outwardly from thetop and bottom of the plate and engage grooves 36 and 37, respectively,formed in the boss 32 along a center line parallel to the axis of thehandle 11. The tabs of the plate are smaller in width than the grooves36 and 37 and afford limited rotation of the rod within an arc of about30 to either side). This allows the handle 12 to tilt slightly relativeto the handle 1 l and provide a comfortable grip for both right andleft-handed users. The spring 17 urges the handle 12 outwardly and holdsthe piston 26 in a selected maximum volume position. The maximum volumeis selected by locating a straight pin portion of a resilient clip 38,as shown in FIG. 6. The straight portion may be inserted in any one of aplurality of transverse holes. In FIG. 4 the pin 38 is shown in the farright hand one of the holes 40 and stops the piston 26 in its minimumsetting. Positioning the pin in each of the other holes will provide forthe discharge of a volume of liquid corresponding to the setting, and,if the clip is removed, a shoulder 41 on the piston acts as the finalsetting for the volume of the cylinder and is the setting for themaximum volume for which the pump may be used.

When the piston moves to the right it tends to compress air within thecylinder between the back of the piston and the closure at the end. Theclosure, however, is provided with ventilating passages because thefitting 30 when seated against the handle 11 in the boss 32 is spacedfrom the end of the right hand cylinder wall a distance sufficient toprovide space around the plate 33 so that air may escape through thisspace into the space within the boss about the fitting 30 and thence outinto the spaces provided by the'slots 36 and 37 and to the atmosphere. Acylindrical center passage in the fitting 30 affords rotation of thefitting about the boss 33a so that the shaft 28 is free to rotate withinthe limited range determined by the clearances between the tabs 34 and35 and the recesses in the boss 32. It will be observed that thepressure of the spring 17 against the pin 38 or against the shoulder 41,depending upon the position of the stop selected, holds the plate 33against the fitting 30 so that a space is maintained between the plateand the end of the cylinder.

The structure of the fitting 15 comprises a main cylindrical block orbase 43 which has been illustrated as having an enlarged opening in itslower end and as threadedly attached to external threads on the boss 16.

Within the boss 16 a nipple 44 is provided which is tapered to fit along tapered internal passage in a base 45 of a needle or piercing tube46 which is securely attached by a press fit or otherwise securelymounted in the base 45. The internal passage of the base as indicated at47 fits over the nipple 44 and extends sufficiently far into the base toprovide a seat for a check valve 48 which is of flexible material and isof the socalled duck bill type. In the position illustrated in FIG. 4this check valve allows flow downardly by separating the engaging lipsof the valve but prevents return of fluid under pressure from below thevalve. When the block 43 is screwed down onto the boss 16 an annularshoulder 50 thereon engages a conical upper wall 51 of the base 45 andthe pressure applied when the base is seated on the nipple maintains anannular seal about the conical wall 51. In this mannerthe space betweenthe base 45 and the interior walls of the boss 16 and base 43 is sealedat both ends against the admission of fluids. The seal provided by theconical wall 51 also separates the passage through the base 43 so thatthe upper portion of the passage indicated at 52, is sealed from thelower portion about the base 45.

When a bottle 14 is placed in the fitting 15 the collar 23 is turned tourge the cam followers or plungers 53 and 54 inwardly to engage theupper edge of the neck flange of the bottle. The plungers 53 and 54 havedownwardly facing surfaces 55 and 56, respectively, which, upon inwardmovement under pressure of the cam surfaces on the collar 23, press thebottle downwardly so that the face of the resilient stopper or seal inthe top of the bottle is urged against an upstanding annular ring 57concentric with the passage 52 in the block 43. The upper portion 52 ofthe passage is thus sealed off both at top and bottom. The constructionof the camming device is shown in enlarged detail in FIG. 5. In the fullline portion of this figure, the plungers 53 and 54 are shown in theirbottle engaging positions; the dotted lines illustrate the retractedpositions of the cams wherein the plungers have been moved outwardly bysprings 58 and 59. The plungers 53 and 54 extend through and slide inbearing openings 61 and 62, respectively, extending through the block43. The block 43 is formed to provide a cylindrical cup 63 in its upperend for receiving the neck of the bottle 14. This cup is formed by anannular upward extension of the block 43 which terminates in an enlargedportion 64 having an outwardly extending flange 65 at its top. Theopenings 61 and 62 for the plungers 53 and 54 are provided in theenlarged portion 64. These openings are enlarged outwardly as indicatedat 66 and 67, respectively, to provide retaining seats for the springs58 and 59. The outer ends of the plungers are provided with relativelythin flat laterally extending rectangular feet or cam engaging portions68 and 69, respectively, which ride on internal cam surfaces of thelocking collar 23.

The locking collar 23 as shown in FIG. 4 comprises a lower annularportion 71 in sliding engagement with the body 43 and which is enlargedabove the portion 71 to provide an annular seat 72 about which areformed the cam surfaces. The collar 23 is retained between the flange 65and a detachable split ring 73 carried in an annular groove in the body43. During the assembly of the fitting 15 the collar 23 is slipped overthe lower end of the base 43 and then the split ring 73 is snapped intothe groove to retain the collar in place.

- The cam followers or plungers 53 and 54 are pressed against theinternal cam surfaces of the collar as shown in FIG. 5, the rectangularfeet 68 and 69 being urged against the cam surfaces and being bentsomewhat circumferentially of the cam surface by the pressure of thecams and springs. The cam surfaces are arcuate and comprise a pair ofdiametrically opposite surfaces 74 and 75 which are concentric with theblock 43 and a second pair of surfaces 76 and 77 extending outwardlyfrom the ends of the surfaces 74 and 75 and which are of a substantiallyshorter radius. The pairs of opposite cams are thus symmetrical abouteach of two axes at 90 to one another. When the counter 23 is turned 90in either direction from its position indicated in full lines in FIG. 5,the surfaces 76 and 77 will be opposite the respective ones of theplungers 53 and 54 and the plungers will move outwardly to their dottedline positions so that their inner ends no longer extend into thecylindrical cup 63 within the wall 64. The bottle can now be removed andreplaced by a fresh bottle.

When a bottle 14 is positioned on the fitting 15 its closure indicatedas comprising a stopper of rubber or other suitable material 78 and ametal collar 79 lies in engagement with the bottom of the cup 63 and thering 57 engages the stopper 78 about the seal piercing tube 46. When thecollar 23 is rotated to move the plungers 53 and 54 inwardly toward theneck of the bottle the sloping surfaces 55 and 56 of the plungers engagethe stopper closure element 79 which extends around the flange of thebottle and presses the bottle downwardly so that the seal 78 is pressedinto firm engagement with the ring 57 and seals the chamber 52 from theatmosphere.

Air is admitted to the chamber 52 through an inlet passage 81 through aduck bill valve 82 which prevents the return of air from the chamber 52through the outlet 81. When the pump handle 12 is released afterdischarging liquid through the passage it is moved to the right by thespring 17 and draws liquid downwardly through the tube 46 and checkvalve 48 and thus removes another charge of liquid from the bottle 14.In order to prevent the reduction of pressure in the bottle 14 and atendency of the liquid not to flow outwardly therefrom air is admittedto the bottle through a passage in a small tube 83 which, asillustrated, is a straight tube extending along the tube 46 andterminating near the top thereof. Both the tubes are tapered to provideseal piercing points and the points lie adjacent one another at the topsof the tubes. It has been found that this arrangement of the liquiddischarge and air inlet tubes effectively prevents the entrainment ofair in the liquid flowing downwardly toward and into the tube 46. Thebubbles coming from the tube 83 tend to rise immediately to the right asviewed in FIG. 4 and the liquid flows downwardly into the tube 46without drawing the bubbles into this downward flow.

For some applications of the dispenser of this invention it may bedesirable to employ a collapsible container instead of the rigid bottle14 and to allow the container to collapse without having to admit airthereto; for this purpose the air tube 83 may be omitted in applicationswhere for any reason the presence of air from the atmosphere mightdeteriorate the quality of the liquid contained in the bottle and makeit unusable. The dispenser of this invention is suitable for use in thetreatment of human patients and the arrangement for utilizing acollapsible container and preventing the admission of air to the vaccineor other liquid may be particularly desirable or required for this useparticularly when the treatment involves the use of a hypodermic needle.

The structural details of the various parts and components of thedispenser are illustrated further in FIGS. 8 and 9, FIG. 9 being anexploded view of the details of construction of the slide 21 forejecting a used discharge tube or cannula as shown in FIGS. 8 and 9. Theslide 21 is preferably molded from synthetic plastic and comprises anelongated member open at the top and of a configuration to fit closelyabout the forward end of the body 10. The front end of the slide isclosed by an upright wall 84 which is provided with an opening 85through which a reduced diameter sleeve 86 on the fitting 18 canproject. When the tube portion or nipple 86 projects through the opening85 a cannula 20 may be pressed into position thereon. The slide isprovided with longitudinal projections 87 extending along the top rearedges of the wall of the slide and which fit into grooves 88, one oneach side of the body 10 directly under the boss 16. The projections 87are shorter then the grooves 88 so that the slide 21 may be moved backand forth while the projections are in the slots and to the extentpermitted by the ends of the slots which act as stops. The slide may bebiased forwardly by a spring 90 which is compressed when a cannula isfitted over the nipple 86 and pressed into place against the front endof the slide. When the cannula is pressed into place over the nipple 86a sear or catch 91 engages a cross slot 92 formed in the bottom of thebody 10 below the rear ends of the slots 88. The catch 91 is mounted ona flexible tongue 93 which carries the trigger 22 and biases it upwardlyor inwardly of the slide, and is securely welded or otherwise bonded tothe forward end of the bottom of the slide 21, attaching lugs or rivets94 being illustrated for this purpose. The trigger 22 extends downwardlyfrom the flexible tongue 93 and when the trigger is pressed forwardly itbends the tongue downwardly and releases the catch 91 from the notch 92whereupon the slide 21 moves forwardly and detaches the cannula. Thespring 90 is not necessary to assure forward movement of the slide 21because the pressure of the operators finger against the trigger 22 willin most applications be sufficient to detach and release the cannula.The trigger 22 is in a position for quick use by the operator holdingthe dispenser in his hand and may direct the used cannula into a wastebasket or other container so that it is not necessary to touch it. Theoperator may then put a new cannula on the device and proceed with thenext use of the dispenser. Thus a large number of individuals may betreated one at a time each with a clean cannula.

For some uses of the dispenser it may be desirable to provide a largervolume of treating liquid than may be conveniently provided in a bottleattached to the dispenser. For such applications, the device illustratedin FIGS. 10 and 11 may be employed instead of the fitting 15. Thisdevice comprises a cap or closure 95 which is screwed onto the boss 16and is provided with an inlet nipple 96 to which a supply conduit 97 maybe attached. The cap 95 is provided with a check valve comprising aflexible disc 98 of synthetic plastic or other suitable material whichis provided with a plurality of holes 100 therethrough in the portionthereof radially outside an annular shoulder 101 formed on .the innertop wall of the cap 95 about the passage within the nipple 96. FIG. 10illustrates the intake position of the valve wherein the drawing offluid into the cylinder 24 has pulled the valve downwardly to permitflow of liquid through the holes 100. When the piston is moved forwardtoward the left as viewed in FIGS. 10 and 11 liquid is forced out thedischarge passage 25 and also up into the chamber within the boss 16,the valve disc 98 is thereby forced upwardly so that the inner portionthereof is pressed against the annular ring 101 and prevents the passageof liquid back into the supply conduit. This supply conduit may beconnected to a suitable source such as a bottle of liquid which may beplaced on the ground or on a convenient support near the operator.

In the operation of the dispenser of this invention standard sizes ofbottles, such as the bottle 14 may be employed and the collar 23 is madeof sufficient size to except a range of sizes of these bottles. Thenecks of the bottles are of the same size and all fit in the cup 63 andare held by the plungers 53 and 54. A minimum loss of liquid isencountered during the course of use of the dispenser, a minor lossbeing due to some leakage of liquid into the passage 52 in the block 43.When starting the operation of the dispenser with a new bottle placed inthe cup 63 and with the piercing tube 46 extending through the stopper78 and into communication with the contents of the bottle a certainamount of air may be trapped in the passages of the dispenser. This airmay be removed by operation of the pump with the discharge end tippedupwardly while the needle is maintained below the surface of liquid inthe bottle 14. The initial pumping can thus remove all air so that thedispenser is ready for use. This initial loading involves some furtherminor loss of liquid. During operation the dispenser is held with thebottle upright and a preset dose is discharged through the passage 25and the cannula or other discharge nozzle secured on the fitting 18. Thevolume to be discharged is determined by placing the pin 38 in aselected one of the holes 40 or by taking the clip 38 out andallowingthe piston to move the full distance of the chamber until theshoulder 41 strikes the plate 33. Access to the clip 38 and the holes 40is had by removing the closure plug 30 and drawing the handle 12outwardly to expose the holes as required. After the selected holeposition has been determined and the clip inserted therein, the closure30 is returned to the position illustrated in FIG. 4 with the plate 33in position and the device is ready for operation at the selectedcapacity. The dosage to be administered by the dispenser is thusdetermined and is not changeable except by removing the closure 30. Thusunintentional or inadvertent changing of the dose to be discharged iseliminated.

Certain vaccines, by way of example, are supplied in vacuum bottles likethe bottle 14 and are the lyophilized vaccines wherein the solids of thevaccine have been dried by freeze drying and then placed in the bottleunder vacuum. To use these vaccines a bottle of sterile water or otherrequired liquid is provided in a sealed bottle such as the bottle 14.The liquid dispenser of this invention facilitates the charging of thevacuum bottle with the liquid to produce the vaccine to be used. Forthis purpose a bottle of water is mounted on the fitting and a standardhypodermic needle placed on the fitting 18. Air is then removed from thedispenser by pumping so that water fills the working passages thereof.The hypodermic needle is then inserted through the seal of the driedvaccine and water is drawn into the vaccine bottle because of thedifferent in pressures between the bottles. The delivery of the fullquantity of water to the vaccine bottle maybe facilitated by utilizingthe pump of the dispenser and full discharge of the water into thevaccine bottle may thus be effected more easily. The vaccine bottle isthen ready for use on the dispenser.

The base 45 of the needle 46 is made with a larger tapered passage thanthe corresponding passage of the standard hypodermic needle. In view ofthis difference in size it is not possible to attach a standard needleto the nipple 44 and thus the operator is assured that the needleattached to the dispensing unit will be a needle 46 and include thecheck valve 48 and prevent the discharge of liquid upwardly through theneedle when mounted on the nipple 44. The base for a hypodermic needleprovided on the fitting 18 is of standard dimensions and will accept thestandard needle.

It will be apparent from the foregoing that the dispenser of thisinvention is useful in a wide range of applications and facilitates thetreatment of a large number of individuals in a substantially reducedperiod of time. To further facilitate the use of the dispenser withminimum likelihood of contact, for example, of one individual with acannula or part of a dispenser which has contacted another individual.The cannula 20 may be provided with a circular disc or shield 102 whichmay be used as a stop member in certain applications, for example, tolimit the movement of the cannula into the nostrial of an animal. Thus,the likelihood of the animals nostril coming into engagement with anypart of the dispenser is minimized and when the used cannula is ejectedthe new cannula for the next animal can be inserted without likelihoodof contacting any part which has contacted another animal. The dispenserof this invention may readily be cleaned and sterilized by autoclaving.

While this invention has been described in connection with a particularembodiment thereof, various modifications will occur to those skilled inthe art. Therefore, it is not desired that the invention be limited tothe specific details of the disclosed device and it is intended by theappended claims to cover all modifications which fall within the spiritand scope of the invention.

We claim:

1. A liquid metering dispenser comprising:

a block having a cylinder open at one end and closed at the other;

a piston slidable in said cylinder between minimum and maximum cylindervolume positions;

means for attaching a liquid supply to said body and including an inletfor delivering liquid to said cylinder adjacent the closed end thereof;

passage means for discharging liquid from said cylinder;

a first handle for holding said body in the hand of an operator;

a second handle connected to said piston and positioned for cooperationwith said first handle for squeezing by hand to move said piston todischarge liquid from said cylinder, said second handle being biased toa position away from said body to urge said piston toward its maximumvolume position;

check valves for preventing reverse passage of liquid through said inletand through said discharge passage means;

said liquid supply attaching means includes a detachable fitting mountedon said body for retaining a bottle of liquid on said body;

means for mounting a bottle seal piercing tube on said body in positionfor piercing the seal of a bottle secured in said fitting whereby saidtube provides a passage between the interior of the bottle and saidcylinder;

said supply attaching means including a boss on said body andsurrounding said inlet, a nipple within said boss about said inlet, saidpiercing tube having a base for detachably engaging said nipple, meansfor adjustably attaching said fitting to said boss and said fittinghaving a passage therethrough about said piercing tube;

said fitting having a shoulder about the passage therein for engagingsaid piercing tube and pressing it into position on said nipple and forsealing the upper portion of said passage from the portion about saidbase;

means for admitting air to said upper portion of said passage; and,

means extending along said piercing tube for conducting air from saidupper portion to a bottle mounted on said fitting when liquid is removedfrom said bottle through said tube.

2. A liquid metering dispenser as set forth in claim 1 wherein saidpassage is of circular configuration and the upper end of said base isconical and engages the wall of the passage in said fitting along anannular sealing line when pressing said base into position on saidnipple.

3. A liquid metering dispenser as set forth in claim 1 wherein saidcheck valve for said inlet is mounted within said base.

4. A liquid metering dispenser as set forth in claim 1 wherein saidfitting includes an upper seat about said passage for receiving the neckof an inverted bottle having its seal pierced by said tube and means fordetachably securing an inverted bottle on said seat. 5. A liquidmetering dispenser as set forth in claim 4 6. A liquid meteringdispenser as set forth in claim 1 including means for sealing said upperportion of said passage and a check valve for preventing the reverseflow of fluid from said upper portion of said passage through said airadmitting means for minimizing reverse flow of fluid through said meansfor conducting air to the bottle.

7. A liquid metering dispenser as set forth in claim 4 wherein saidlocking members comprise pins slidable in said fitting toward and awayfrom a bottle on said seat, said members including springs urging themtoward said collar,

said collar having cam surfaces on its inner face for moving saidmembers inwardly for engaging a bottle neck on said seat and saidmembers having sloping surfaces for engaging the neck flange of a bottle6 and urging the bottle downward against said seat.

8. A liquid metering dispenser comprising:

a block having a cylinder open at one end and closed at the other;

a piston slidable in said cylinder between minimum and maximum cylindervolume positions;

means for attaching a liquid supply to said body and including an inletfor delivering liquid to said cylinder adjacent the closed end thereof;

passage means for discharging liquid from said cylinder;

a first handle for holding said body in the hand of an operator;

a second handle connected to said piston and positioned for cooperationwith said first handle for squeezing by hand to move said piston todischarge liquid from said cylinder, said second handle being biased toa position away from said body to urge said piston toward its maximumvolume position;

check valves for preventing reverse passage of liquid through said inletand through said discharge passage means;

said connection between said handle and said piston comprising a rod;

closure means slidably engaging said rod and detachably secured to saidbody for closing the open end of said cylinder and for guiding said rod;

stop means on said rod between said piston and said closure means andpositioned for engagement with said closure means for determining thelimit of outward movement of said piston;

means for adjusting the position of said stop means to selectivelydetermine the volume of liquid to be discharged from said cylinder, saidadjusting means being accessible upon removal of said closure means fromsaid body; and,

said stop means comprising spaced holes in said rod and a clip forengaging the selected hole and for engaging said closure means in theselected maximum volume position of said piston.

9. A liquid metering dispenser comprising:

a block having a cylinder open at one end and closed at the other;

a piston slidable in said cylinder between minimum and maximum cylindervolume positions;

means for attaching a liquid supply to said body and including an inletfor delivering liquid to said cylinder adjacent the closed end thereof;

passage means for discharging liquid from said cylinder;

a first handle for holding said body in the hand of an operator;

a second handle connected to said piston and posi tioned for cooperationwith said first handle for squeezing by hand to move said piston todischarge liquid from said cylinder, said second handle being biased toa position away from said body to urge said piston toward its maximumvolume position;

check valves for preventing reverse passage of liquid through said inletand through said discharge passage means;

means for the quick attaching of selected discharge fittings to theoutlet from said body; and,

means for quick detachment of discharge fittings from said dispenserwhile holding the handle thereof, said detaching means comprising:

slip means for mounting a cannula or the like on the outlet of saidbody,

a release member slidably mounted on said body and movable toward andaway from the outlet end thereof,

means for locking said release member in its position nearest saidoutlet end, and

means adjacent said handle for releasing said lock means while holdingsaid dispenser by said handle and for pushing the cannula out ofengagement with said slip means to detach the cannula from saiddispenser.

10. A liquid metering dispenser as set forth in claim 9 and a pluralityof said cannulas, each comprising a tube having thereon a transversedisc for limiting the distance of penetration of the tube into a cavityto be treated whereby contact of the dispenser body and a treatedindividual is prevented and the plurality of cannulas may be used eachin turn on separate individuals without contamination from previoustreatments.

11. A liquid metering dispenser comprising:

a block having a cylinder open at one end and closed at the other;

a piston slidable in said cylinder between minimum and maximum cylindervolume positions;

means for attaching a liquid supply to said body and including an inletfor delivering liquid to said cylinder adjacent the closed end thereof;

passage means for discharging liquid from said cylinder;

a first handle for holding said body in the hand of an operator;

a second handle connected to said piston and positioned for cooperationwith said first handle for squeezing by hand to move said piston todischarge liquid from said cylinder, said second handle being biased toa position away from said body to urge said piston toward its maximumvolume position;

check valves for preventing reverse passage of liquid through said inletand through said discharge passage means;

said liquid supply attaching means includes a detachable fitting mountedon said body for retaining a bottle of liquid on said body;

means for mounting a bottle seal-piercing tube onsaid body in positionfor piercing the seal of a bottle secured in said fitting whereby saidtube provides a passage between the interior of the bottle and saidcylinder;

said supply attaching means including a boss on said body andsurrounding said inlet, and a nipple within said boss about said inlet,said piercing tube having a base for detachably engaging said nipple,means for adjustably attaching said fitting to said boss and saidfitting having a passage therethrough about said piercing tube; and,

said fitting having a shoulder about the passage therein for engagingsaid piercing tube and pressing it into position on said nipple and forsealing the upper portion of said passage from the portion about saidbase.

12. A liquid metering dispenser as set forth in claim 11 wherein:

said connection between said handle and said piston comprises a rod,

closure means slidably engaging said rod and detachably secured to saidbody for closing the open end of said cylinder and for guiding said rod,

stop means on said rod between said piston and said closure means andpositioned for engagement with said closure means for determining thelimit of outward movement of said piston, and

means for adjusting the position of said stop means to selectivelydetermine the volume of liquid to be discharged from said cylinder, saidadjusting means being accessible upon removal of said closure means fromsaid body.

13. A liquid metering dispenser as set forth in claim 11 including meansfor attaching a standard hypodermic needle at the outlet of said bodywhereby said dispenser may be utilized as a hypodermic syringe.

14. A liquid metering dispenser as set forth in claim 13 wherein saidmounting means for said piercing tube is of a size different from thatfor a standard hypodermic needle whereby said standard needle and saidpiercing tube are not interchangeable.

1. A liquid metering dispenser comprising: a block having a cylinderopen at one end and closed at the other; a piston slidable in saidcylinder between minimum and maximum cylinder volume positions; meansfor attaching a liquid supply to said body and including an inlet fordelivering liquid to said cylinder adjacent the closed end thereof;passage means for discharging liquid from said cylinder; a first handlefor holding said body in the hand of an operator; a second handleconnected to said piston and positioned for cooperation with said firsthandle for squeezing by hand to move said piston to discharge liquidfrom said cylinder, said second handle being biased to a position awayfrom said body to urge said piston toward its maximum volume position;check valves for preventing reverse passage of liquid through said inletand through said discharge passage means; said liquid supply attachingmeans includes a detachable fitting mounted on said body for retaining abottle of liquid on said body; means for mounting a bottle seal piercingtube on said body in position for piercing the seal of a bottle securedin said fitting whereby said tube provides a passage between theinterior of the bottle and said cylinder; said supply attaching meansincluding a boss on said body and surrounding said inlet, a nipplewithin said boss about said inlet, said piercing tube having a base fordetachably engaging said nipple, means for adjustably attaching saidfitting to said boss and said fitting having a passage therethroughabout said piercing tube; said fitting having a shoulder about thepassage therein for engaging said piercing tube and pressing it intoposition on said nipple and for sealing the upper portion of saidpassage from the portion about said base; means for admitting air tosaid upper portion of said passage; and, means extending along saidpiercing tube for conducting air from said upper portion to a bottlemounted on said fitting when liquid is removed from said bottle throughsaid tube.
 2. A liquid metering dispenser as set forth in claim 1wherein said passage is of circular configuration and the upper end ofsaid base is conical and engages the wall of the passage in said fittingalong an annular sealing line when pressing said base into position onsaid nipple.
 3. A liquid metering dispenser as set forth in claim 1wherein said check valve for said inlet is mounted within said base. 4.A liquid metering dispenser as set forth in claim 1 wherein said fittingincludes an upper seat about said passage for receiving the neck of aninverted bottle having its seal pierced by said tube and means fordetachably securing an inverted bottle on said seat.
 5. A liquidmetering dispenser as set forth in claim 4 wherein said means fordetachably securing a bottle on said seat comprises a plurality oflocking members mounted in said fitting and a collar rotatably mountedon said fitting and positioned for engagement with and actuation of saidlocking members to move said members into engagement with the bottle. 6.A liquid metering dispenser as set forth in claim 1 including means forsealing said upper portion of said passage and a check valve forpreventing the reverse flow of fluid from said upper portion of saidpassage through said air admitting means for minimizing reverse flow offluid thrOugh said means for conducting air to the bottle.
 7. A liquidmetering dispenser as set forth in claim 4 wherein said locking memberscomprise pins slidable in said fitting toward and away from a bottle onsaid seat, said members including springs urging them toward saidcollar, said collar having cam surfaces on its inner face for movingsaid members inwardly for engaging a bottle neck on said seat and saidmembers having sloping surfaces for engaging the neck flange of a bottleand urging the bottle downward against said seat.
 8. A liquid meteringdispenser comprising: a block having a cylinder open at one end andclosed at the other; a piston slidable in said cylinder between minimumand maximum cylinder volume positions; means for attaching a liquidsupply to said body and including an inlet for delivering liquid to saidcylinder adjacent the closed end thereof; passage means for dischargingliquid from said cylinder; a first handle for holding said body in thehand of an operator; a second handle connected to said piston andpositioned for cooperation with said first handle for squeezing by handto move said piston to discharge liquid from said cylinder, said secondhandle being biased to a position away from said body to urge saidpiston toward its maximum volume position; check valves for preventingreverse passage of liquid through said inlet and through said dischargepassage means; said connection between said handle and said pistoncomprising a rod; closure means slidably engaging said rod anddetachably secured to said body for closing the open end of saidcylinder and for guiding said rod; stop means on said rod between saidpiston and said closure means and positioned for engagement with saidclosure means for determining the limit of outward movement of saidpiston; means for adjusting the position of said stop means toselectively determine the volume of liquid to be discharged from saidcylinder, said adjusting means being accessible upon removal of saidclosure means from said body; and, said stop means comprising spacedholes in said rod and a clip for engaging the selected hole and forengaging said closure means in the selected maximum volume position ofsaid piston.
 9. A liquid metering dispenser comprising: a block having acylinder open at one end and closed at the other; a piston slidable insaid cylinder between minimum and maximum cylinder volume positions;means for attaching a liquid supply to said body and including an inletfor delivering liquid to said cylinder adjacent the closed end thereof;passage means for discharging liquid from said cylinder; a first handlefor holding said body in the hand of an operator; a second handleconnected to said piston and positioned for cooperation with said firsthandle for squeezing by hand to move said piston to discharge liquidfrom said cylinder, said second handle being biased to a position awayfrom said body to urge said piston toward its maximum volume position;check valves for preventing reverse passage of liquid through said inletand through said discharge passage means; means for the quick attachingof selected discharge fittings to the outlet from said body; and, meansfor quick detachment of discharge fittings from said dispenser whileholding the handle thereof, said detaching means comprising: slip meansfor mounting a cannula or the like on the outlet of said body, a releasemember slidably mounted on said body and movable toward and away fromthe outlet end thereof, means for locking said release member in itsposition nearest said outlet end, and means adjacent said handle forreleasing said lock means while holding said dispenser by said handleand for pushing the cannula out of engagement with said slip means todetach the cannula from said dispenser.
 10. A liquid metering dispenseras set forth in claim 9 and a plurality of said cannulas, eachcOmprising a tube having thereon a transverse disc for limiting thedistance of penetration of the tube into a cavity to be treated wherebycontact of the dispenser body and a treated individual is prevented andthe plurality of cannulas may be used each in turn on separateindividuals without contamination from previous treatments.
 11. A liquidmetering dispenser comprising: a block having a cylinder open at one endand closed at the other; a piston slidable in said cylinder betweenminimum and maximum cylinder volume positions; means for attaching aliquid supply to said body and including an inlet for delivering liquidto said cylinder adjacent the closed end thereof; passage means fordischarging liquid from said cylinder; a first handle for holding saidbody in the hand of an operator; a second handle connected to saidpiston and positioned for cooperation with said first handle forsqueezing by hand to move said piston to discharge liquid from saidcylinder, said second handle being biased to a position away from saidbody to urge said piston toward its maximum volume position; checkvalves for preventing reverse passage of liquid through said inlet andthrough said discharge passage means; said liquid supply attaching meansincludes a detachable fitting mounted on said body for retaining abottle of liquid on said body; means for mounting a bottle seal piercingtube on said body in position for piercing the seal of a bottle securedin said fitting whereby said tube provides a passage between theinterior of the bottle and said cylinder; said supply attaching meansincluding a boss on said body and surrounding said inlet, and a nipplewithin said boss about said inlet, said piercing tube having a base fordetachably engaging said nipple, means for adjustably attaching saidfitting to said boss and said fitting having a passage therethroughabout said piercing tube; and, said fitting having a shoulder about thepassage therein for engaging said piercing tube and pressing it intoposition on said nipple and for sealing the upper portion of saidpassage from the portion about said base.
 12. A liquid meteringdispenser as set forth in claim 11 wherein: said connection between saidhandle and said piston comprises a rod, closure means slidably engagingsaid rod and detachably secured to said body for closing the open end ofsaid cylinder and for guiding said rod, stop means on said rod betweensaid piston and said closure means and positioned for engagement withsaid closure means for determining the limit of outward movement of saidpiston, and means for adjusting the position of said stop means toselectively determine the volume of liquid to be discharged from saidcylinder, said adjusting means being accessible upon removal of saidclosure means from said body.
 13. A liquid metering dispenser as setforth in claim 11 including means for attaching a standard hypodermicneedle at the outlet of said body whereby said dispenser may be utilizedas a hypodermic syringe.
 14. A liquid metering dispenser as set forth inclaim 13 wherein said mounting means for said piercing tube is of a sizedifferent from that for a standard hypodermic needle whereby saidstandard needle and said piercing tube are not interchangeable.